Sodium citrate do no harm to people since the raw material is basically from grain. The Food and Agriculture of the United Nations and the World Health Organization make no restriction on its daily intake, which can be considered to be drug-free.

Sodium citrate is diluted by a large amount of water in nature, and part of which becomes citric acid, and the two coexist in the same system. Citric acid is easily biodegraded by oxygen, heat, light, bacteria and microorganisms in water.

Sodium citrate has good complexation ability for Ca2+, Mg2+ and other metal ions, and also has good complexation ability for other metal ions, such as Fe2+ plasma.

Sodium citrate has good pH regulation and buffering properties. Sodium citrate and citric acid can form a strong pH buffer, so it is important in some situations where a wide range of pH changes are not allowed.